Rapid genotype imputation from sequence with reference panels

Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole-genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Davies, RW, Kucka, M, Su, D, Shi, S, Flanaghan, M, Cunniff, CM, Chan, YF, Myers, S
פורמט: Journal article
שפה:English
יצא לאור: Springer Nature 2021