Rapid genotype imputation from sequence with reference panels
Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole-genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2021
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