Rapid genotype imputation from sequence with reference panels

Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole-genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Davies, RW, Kucka, M, Su, D, Shi, S, Flanaghan, M, Cunniff, CM, Chan, YF, Myers, S
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Springer Nature 2021