Rapid genotype imputation from sequence with reference panels
Inexpensive genotyping methods are essential to modern genomics. Here we present QUILT, which performs diploid genotype imputation using low-coverage whole-genome sequence data. QUILT employs Gibbs sampling to partition reads into maternal and paternal sets, facilitating rapid haploid imputation usi...
Main Authors: | Davies, RW, Kucka, M, Su, D, Shi, S, Flanaghan, M, Cunniff, CM, Chan, YF, Myers, S |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Springer Nature
2021
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