Computationally profiling peptide: MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
<p>T-cell receptor-mimetic antibodies (TCRms) targeting disease-associated peptides presented by Major Histocompatibility Complexes (pMHCs) are set to become a major new drug modality. However, we lack a general understanding of how TCRms engage pMHC targets, which is crucial for predicting th...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2023
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