MHC class i-restricted cytotoxic lymphocyte responses induced by enterotoxin-based mucosal adjuvants

<p style="text-align:justify;">The ability of enterotoxin-based mucosal adjuvants to induce CD8+ MHC class I-restricted CTL responses to a codelivered bystander Ag was examined. Escherichia coli heat-labile toxin (LT), or derivatives of LT carrying mutations in the A subunit (LTR72,...

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Autors principals: Simmons, C, Mastroeni, P, Fowler, R, Ghaem-Maghami, M, Lycke, N, Pizza, M, Rappuoli, R, Dougan, G
Format: Journal article
Idioma:English
Publicat: American Association of Immunologists 1999