Quantitating T cell cross-reactivity for unrelated peptide antigens.

Quantitating the frequency of T cell cross-reactivity to unrelated peptides is essential to understanding T cell responses in infectious and autoimmune diseases. Here we used 15 mouse or human CD8+ T cell clones (11 antiviral, 4 anti-self) in conjunction with a large library of defined synthetic pep...

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Bibliographic Details
Main Authors: Ishizuka, J, Grebe, K, Shenderov, E, Peters, B, Chen, Q, Peng, Y, Wang, L, Dong, T, Pasquetto, V, Oseroff, C, Sidney, J, Hickman, H, Cerundolo, V, Sette, A, Bennink, JR, McMichael, A, Yewdell, J
Format: Journal article
Language:English
Published: 2009