Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk.

Recent studies have reported that regions of homozygosity (ROH) in the genome are detectable in outbred populations and can be associated with an increased risk of malignancy. To examine whether homozygosity is associated with an increased risk of developing childhood B-cell precursor acute lymphobl...

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Bibliographic Details
Main Authors: Hosking, F, Papaemmanuil, E, Sheridan, E, Kinsey, SE, Lightfoot, T, Roman, E, Irving, J, Allan, J, Taylor, M, Tomlinson, I, Greaves, M, Houlston, R
Format: Journal article
Language:English
Published: 2010