Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction

Chemokines mediate leucocyte migration and homeostasis, and are key targets in inflammatory diseases including atherosclerosis, cytokine storm and chronic auto-immune disease. Chemokine redundancy and ensuing network robustness has frustrated therapeutic development. Salivary evasins from ticks bind...

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Bibliographic Details
Main Authors: Darlot, B, Eaton, JRO, Geis-Asteggiante, L, Yakala, GK, Karuppanan, K, Davies, G, Robinson, CV, Kawamura, A, Bhattacharya, S
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2020