SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC to be described, harbours multiple amino acid...

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Bibliographic Details
Main Authors: Willett, BJ, Grove, J, MacLean, OA, Klenerman, P, Dunachie, S, Barnes, E, Brown, A, Adele, S, Kronsteiner, B, Murray, SM, Abraham, P, Deeks, A, Ansari, MA, Fraser, C, Bonsall, D, Fryer, H, Lythgoe, K, Thomson, L, Golubchik, T, Underwood, AP, Taylor, BEW, Yeats, CA, Aanensen, DM, Abudahab, K, Menegazzo, M, Zarebski, AE, Gutierrez, B, Raghwani, J, du Plessis, L, Kraemer, MUG, Pybus, OG, Francois, S, Attwood, SW, Vasylyeva, TI, Trebes, A, Green, A, Buck, D, MacIntyre-Cockett, G, Todd, JA
Other Authors: PITCH Consortium
Format: Journal article
Language:English
Published: Springer Nature 2022
Subjects:
molecular biology
immunology
vaccines
viral infection

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