A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis
Chronic hepatitis B is one of the world's unconquered diseases with more than 240 million infected subjects at risk of developing liver disease and hepatocellular carcinoma. Hepatitis B virus reverse transcribes pre-genomic RNA to relaxed circular DNA (rcDNA) that comprises the infectious parti...
Main Authors: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
Life Science Alliance
2019
|