Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.

Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.

Transcription factors (TFs) act within wider regulatory networks to control cell identity and fate. Numerous TFs, including Scl (Tal1) and PU.1 (Spi1), are known regulators of developmental and adult haematopoiesis, but how they act within wider TF networks is still poorly understood. Transcription...

Full description

Bibliographic Details
Main Authors: Wilkinson, A, Kawata, V, Schütte, J, Gao, X, Antoniou, S, Baumann, C, Woodhouse, S, Hannah, R, Tanaka, Y, Swiers, G, Moignard, V, Fisher, J, Hidetoshi, S, Tijssen, MR, de Bruijn, M, Liu, P, Göttgens, B
Format: Journal article
Language:English
Published: Company of Biologists Ltd 2014

Similar Items