Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8.

AIMS/HYPOTHESIS: Genetic investigations in the spontaneously diabetic (Type 2) Goto Kakizaki (GK) rat have identified quantitative trait loci (QTL) for diabetes-related phenotypes. The aims of this study were to refine the chromosomal mapping of a QTL ( Nidd/gk5) identified in chromosome 8 of the G...

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Bibliographic Details
Main Authors: Wallis, R, Wallace, K, Collins, S, McAteer, M, Argoud, K, Bihoreau, M, Kaisaki, P, Gauguier, D
Format: Journal article
Language:English
Published: 2004