The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming

The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming

Conversion of promoter-proximally paused RNA polymerase II (RNAPII) into elongating polymerase by the positive transcription elongation factor b (P-TEFb) is a central regulatory step of mRNA synthesis. The activity of P-TEFb is controlled mainly by the 7SK small nuclear ribonucleoprotein (snRNP), wh...

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Bibliographische Detailangaben
Hauptverfasser:	Studniarek, C, Tellier, M, Martin, PGP, Murphy, S, Kiss, T, Egloff, S
Format:	Journal article
Sprache:	English
Veröffentlicht:	Cell Press 2021

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