Targeting FRET-based reporters for cAMP and PKA activity using AKAP79

Fluorescence resonance energy transfer (FRET)-based sensors for 3′–5′cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) allow real-time imaging of cAMP levels and kinase activity in intact cells with high spatiotemporal resolution. The development of FRET-based sensors has made it poss...

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Bibliographic Details
Main Authors: Zaccolo, M, Musheshe, N, Lobo, M, Schmidt, M
Format: Journal article
Published: MDPI 2018