Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.

Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pressure-bearing sites of the mammalian footpad. It can be induced in hyperproliferative states such as wound healing, inflammation and cancer. Here we show that the inactive rhomboid protease RHBDF2 (iRHOM2) regulates thicke...

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Bibliographic Details
Main Authors: Maruthappu, T, Chikh, A, Fell, B, Delaney, P, Brooke, M, Levet, C, Moncada-Pazos, A, Ishida-Yamamoto, A, Blaydon, D, Waseem, A, Leigh, I, Freeman, M, Kelsell, D
Format: Journal article
Language:English
Published: Springer Nature 2017