Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger

The understanding of biomolecular recognition of posttranslationally modified histone proteins is centrally important to the histone code hypothesis. Despite extensive binding and structural studies on the readout of histones, the molecular language by which posttranslational modifications on histon...

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Príomhchruthaitheoirí: Pieters, BJGE, Wuts, MHM, Poater, J, Kumar, K, White, PB, Kamps, JJAG, Sherman, W, Pruijn, GJM, Paton, RS, Beuming, T, Bickelhaupt, FM, Mecinovic, J
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Nature Research 2020