Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells.

The first step in the induction of immune responses, whether humoral or cell mediated, requires the interaction between antigen-presenting cells and T lymphocytes restricted at the major histocompatibility complex (MHC). These cells invariably express MHC class II molecules (HLA-D region in man and...

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Bibliographic Details
Main Authors: Londei, M, Lamb, JR, Bottazzo, G, Feldmann, M
Format: Journal article
Language:English
Published: 1984