Genetic composition of replication competent clonal HIV-1 variants isolated from peripheral blood mononuclear cells (PBMC), HIV-1 proviral DNA from PBMC and HIV-1 RNA in serum in the course of HIV-1 infection.

The HIV-1 quasispecies in peripheral blood mononuclear cells (PBMC) is considered to be a mix of actively replicating, latent, and archived viruses and may be genetically distinct from HIV-1 variants in plasma that are considered to be recently produced. Here we analyzed the genetic relationship bet...

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Bibliographic Details
Main Authors: Edo-Matas, D, van Gils, M, Bowles, E, Navis, M, Rachinger, A, Boeser-Nunnink, B, Stewart-Jones, G, Kootstra, N, van 't Wout, AB, Schuitemaker, H
Format: Journal article
Language:English
Published: 2010