Investigating the biology of nuclear IGF-1R in prostate cancer
<p>Insulin-like growth factor 1 receptor (IGF-1R) is a transmembrane receptor tyrosine kinase comprised of two extracellular α- and two transmembrane β-subunits in a heterotetrameric structure. IGF-axis signalling is implicated in cancer progression, metastasis and resistance to treatment incl...
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Format: | Thesis |
Language: | English |
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2021
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