O-substituted alkyl aldehydes for rhodium-catalyzed intermolecular alkyne hydroacylation: the utility of methylthiomethyl ethers.

O-substituted alkyl aldehydes for rhodium-catalyzed intermolecular alkyne hydroacylation: the utility of methylthiomethyl ethers.

Combining α-methylthiomethyl (MTM) ether substituted aldehydes and 1-alkynes in the presence of [Rh(dppe)]ClO(4) results in efficient intermolecular alkyne hydroacylation to deliver α-O-MTM-substituted enone products. The product MTM ethers can be converted to the free hydroxyl group either in situ,...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Parsons, SR, Hooper, J, Willis, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2011

Documenti analoghi

Traceless chelation-controlled rhodium-catalyzed intermolecular alkene and alkyne hydroacylation.
di: Hooper, J, et al.
Pubblicazione: (2013)

Rhodium-catalyzed intermolecular chelation controlled alkene and alkyne hydroacylation: synthetic scope of beta-S-substituted aldehyde substrates.
di: Willis, M, et al.
Pubblicazione: (2006)

Rhodium (I) catalyzed intermolecular hydroacylation.
di: Sapmaz, S, et al.
Pubblicazione: (2001)

Rhodium-catalysed intermolecular alkyne hydroacylation: the enantioselective synthesis of α- and β-substituted ketones by kinetic resolution.
di: González-Rodríguez, C, et al.
Pubblicazione: (2010)

Exploiting carbonyl groups to control intermolecular rhodium-catalyzed alkene and alkyne hydroacylation
di: Coxon, TJ, et al.
Pubblicazione: (2017)

Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation
di: Willis, M, et al.
Pubblicazione: (2016)

α‐Amidoaldehydes as substrates in rhodium‐catalyzed intermolecular alkyne hydroacylation: The synthesis of α‐Amidoketones
di: Pal, R, et al.
Pubblicazione: (2020)

a-Amidoaldehydes as substrates in rhodium-catalyzed intermolecular alkyne hydroacylation: The synthesis of a-amidoketones
di: Pal, R, et al.
Pubblicazione: (2020)

Rhodium-catalyzed enantioselective intermolecular hydroacylation reactions
di: Gonzalez-Rodriguez, C, et al.
Pubblicazione: (2011)

Exploring Small Bite-Angle Ligands for the Rhodium-Catalyzed Intermolecular Hydroacylation of beta-S-Substituted Aldehydes with 1-Octene and 1-Octyne
di: Pernik, I, et al.
Pubblicazione: (2012)

Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation
di: Moseley, D
Pubblicazione: (2022)

An enamine controlling group for rhodium-catalyzed intermolecular hydroacylation
di: Straker, R, et al.
Pubblicazione: (2018)

Chelation-controlled intermolecular alkene and alkyne hydroacylation: the utility of beta-thioacetal aldehydes.
di: Willis, M, et al.
Pubblicazione: (2005)

α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation
di: Hooper, JF, et al.
Pubblicazione: (2016)

Exploring small bite-angle PNP and PCP ligands for the rhodium-catalysed intermolecular hydroacylation of b-s-substituted aldehydes with alkenes and alkynes
di: Pernik, I
Pubblicazione: (2014)

Traceless rhodium-catalyzed hydroacylation using alkyl aldehydes: the enantioselective synthesis of β-aryl ketones
di: Willis, M, et al.
Pubblicazione: (2016)

Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes.
di: Osborne, J, et al.
Pubblicazione: (2008)

2-Aminobenzaldehydes as versatile substrates for rhodium-catalyzed alkyne hydroacylation: application to dihydroquinolone synthesis.
di: Castaing, M, et al.
Pubblicazione: (2013)

Replacing dichloroethane as a solvent for rhodium-catalysed intermolecular alkyne hydroacylation reactions: the utility of propylene carbonate
di: Lenden, P, et al.
Pubblicazione: (2011)

Rhodium-catalysed linear-selective alkyne hydroacylation.
di: Poingdestre, S, et al.
Pubblicazione: (2012)

Chelation-controlled intermolecular hydroacylation: direct addition of alkyl aldehydes to functionalized alkenes.
di: Willis, M, et al.
Pubblicazione: (2004)

Rhodium-catalyzed branched-selective alkyne hydroacylation: a ligand-controlled regioselectivity switch.
di: González-Rodríguez, C, et al.
Pubblicazione: (2011)

Intermolecular rhodium catalyzed hydroacylation of allenes: the regioselective synthesis of beta,gamma-unsaturated ketones
di: Randell-Sly, H, et al.
Pubblicazione: (2009)

Intermolecular alkene and alkyne hydroacylation with beta-S-substituted aldehydes: mechanistic insight into the role of a hemilabile P-O-P ligand.
di: Moxham, G, et al.
Pubblicazione: (2008)

Mechanistic studies of rhodium-catalysed intermolecular hydroacylation
di: Barwick-Silk, J
Pubblicazione: (2018)

Transition metal catalyzed alkene and alkyne hydroacylation.
di: Willis, M
Pubblicazione: (2010)

Intermolecular hydroacylation: high activity rhodium catalysts containing small-bite-angle diphosphine ligands.
di: Chaplin, AB, et al.
Pubblicazione: (2012)

Controlling selectivity in the rhodium-catalysed intermolecular hydroacylation reaction
di: Pawley, R
Pubblicazione: (2012)

Controlling Selectivity in Intermolecular Alkene or Aldehyde Hydroacylation Reactions Catalyzed by {Rh(L-2)}(+) Fragments
di: Pawley, R, et al.
Pubblicazione: (2010)

An alkyne hydroacylation route to highly substituted furans.
di: Lenden, P, et al.
Pubblicazione: (2011)

A second-generation catalyst for intermolecular hydroacylation of alkenes and alkynes using beta-S-substituted aldehydes: the role of a hemilabile P-O-P ligand.
di: Moxham, G, et al.
Pubblicazione: (2006)

Tandem catalytic processes involving Rhodium-catalysed intermolecular hydroacylation
di: Lenden, P
Pubblicazione: (2011)

Azine N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation
di: Moseley, DF, et al.
Pubblicazione: (2021)

Hydroacylation of Alkenes, Alkynes, and Allenes
di: Willis, M
Pubblicazione: (2014)

Intermolecular Alkyne Hydroacylation. Mechanistic Insight from the Isolation of the Vinyl Intermediate That Precedes Reductive Elimination
di: Pawley, R, et al.
Pubblicazione: (2012)

Rh(DPEPhos)-catalyzed alkyne hydroacylation using β-carbonyl-substituted aldehydes: mechanistic insight leads to low catalyst loadings that enables selective catalysis on gram-scale
di: Barwick-Silk, J, et al.
Pubblicazione: (2018)

Enantioselective three-component assembly of β’-aryl-enones using a rhodium-catalyzed alkyne hydroacylation/aryl boronic acid conjugate addition sequence
di: Gao, M, et al.
Pubblicazione: (2017)

Two-component assembly of thiochroman-4-ones and tet-rahydrothiopyran-4-ones using a rhodium-catalyzed alkyne hydroacylation/thio-conjugate-addition sequence
di: Willis, M, et al.
Pubblicazione: (2016)

Sequential catalysis: Exploiting a single rhodium(I) catalyst to promote an alkyne hydroacylation–aryl boronic acid conjugate addition sequence
di: Fernández, M, et al.
Pubblicazione: (2016)

Ketone synthesis via rhodium-catalyzed traceless chelation-controlled hydroacylation reactions
di: Gao, M
Pubblicazione: (2018)