"Null" HLA A*0101 mutation identified in a colorectal cancer cell line

Cancer cells with the Replication Repair defect (RER) are subject to frequent errors, during DNA replication, particularly in DNA sequences with either single or double base pair repeats. Such a single base pair repeat occurs in the HLA*0101 gene, at the beginning of Exon 4 (bp 621-627), where a run...

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Autors principals: Bicknell, D, Bodmer, W
Format: Journal article
Idioma:English
Publicat: 2001