Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes.

Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes.

Early and high-level production of IL-12 is crucial for effective immune responses against pathogens. Up until now, the cells providing this initial IL-12 have remained elusive. Here we show that a subset of human blood dendritic cells (DC) is the principal and primary source of IL-12p70 when blood...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Schäkel, K, von Kietzell, M, Hänsel, A, Ebling, A, Schulze, L, Haase, M, Semmler, C, Sarfati, M, Barclay, N, Randolph, G, Meurer, M, Rieber, E
Format: Journal article
Sprache:English
Veröffentlicht: 2006

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