Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype.
Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disorders and the mechanism of action of antidepressant drugs. However, the relationship between BDNF and serotonergic signalling is poorly understood. Heterozygous mutants BDNF +/- mice were utilized to in...
Glavni autori: | , , , , , , , , , , , , |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2008
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