Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype.

Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disorders and the mechanism of action of antidepressant drugs. However, the relationship between BDNF and serotonergic signalling is poorly understood. Heterozygous mutants BDNF +/- mice were utilized to in...

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Bibliografski detalji
Glavni autori: Guiard, B, David, D, Deltheil, T, Chenu, F, Le Maître, E, Renoir, T, Leroux-Nicollet, I, Sokoloff, P, Lanfumey, L, Hamon, M, Andrews, A, Hen, R, Gardier, A
Format: Journal article
Jezik:English
Izdano: 2008