CD8+ T cell-mediated suppression of intracellular Mycobacterium tuberculosis growth in activated human macrophages.

Animal models of tuberculosis point to a protective role for MHC class I-restricted CD8(+) T cells, yet it is unclear how these cells protect or whether such findings extend to humans. Here we report that macrophages infected with Mycobacterium tuberculosis, rapidly process and present an early secr...

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Detalhes bibliográficos
Principais autores: Brookes, R, Pathan, A, Mcshane, H, Hensmann, M, Price, D, Hill, A
Formato: Journal article
Idioma:English
Publicado em: 2003