Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

PURPOSE: Tumor hypoxia is known to be associated with resistance to chemotherapy, radiotherapy, and poorer survival. Recently, it is shown that hypoxia induces the expression of hypoxia-inducible factor-1alpha and 2alpha (HIF-1alpha and HIF-2alpha), which then up-regulates the expression of downstr...

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Detaylı Bibliyografya
Asıl Yazarlar: Hui, E, Chan, A, Pezzella, F, Turley, H, To, K, Poon, T, Zee, B, Mo, F, Teo, P, Huang, D, Gatter, K, Johnson, P, Harris, A
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2002