Killer cell lectin-like receptor G1 inhibits NK cell function through activation of Adenosine 5'-monophosphate-activated protein kinase

NK cells are the first line of defense against infected and transformed cells. Defective NK cell activity was shown to increase susceptibility for viral infections and reduce tumor immune-surveillance. With age, the incidence of infectious diseases and malignancy rises dramatically, suggesting that...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Müller-Durovic, B, Lanna, A, Polaco Covre, L, Mills, R, Henson, S, Akbar, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: American Association of Immunologists 2016