Killer cell lectin-like receptor G1 inhibits NK cell function through activation of Adenosine 5'-monophosphate-activated protein kinase

NK cells are the first line of defense against infected and transformed cells. Defective NK cell activity was shown to increase susceptibility for viral infections and reduce tumor immune-surveillance. With age, the incidence of infectious diseases and malignancy rises dramatically, suggesting that...

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Détails bibliographiques
Auteurs principaux: Müller-Durovic, B, Lanna, A, Polaco Covre, L, Mills, R, Henson, S, Akbar, A
Format: Journal article
Langue:English
Publié: American Association of Immunologists 2016