Endogenous control of immunity against infection: tenascin-C regulates TLR4-mediated inflammation via microRNA-155.

Endogenous molecules generated upon pathogen invasion or tissue damage serve as danger signals that activate host defense; however, their precise immunological role remains unclear. Tenascin-C is an extracellular matrix glycoprotein that is specifically induced upon injury and infection. Here, we sh...

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Bibliographic Details
Main Authors: Piccinini, A, Midwood, K
Format: Journal article
Language:English
Published: 2012