T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Genome-wide association studies have identified noncoding variants near TBX3 that are associated with PR interval and QRS duration, suggesting that subtle changes in TBX3 expression affect atrioventricular conduction system function. To explore whether and to what extent the atrioventricular conduct...

書誌詳細
主要な著者:	Mohan, RA, Bosada, FM, van Weerd, JH, van Duijvenboden, K, Wang, J, Mommersteeg, MTM, Hooijkaas, IB, Wakker, V, de Gier-de Vries, C, Coronel, R, Boink, GJJ, Bakkers, J, Barnett, P, Boukens, BJ, Christoffels, VM
フォーマット:	Journal article
言語:	English
出版事項:	National Academy of Sciences 2020

類似資料

Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.
著者:: Bakker, M, 等
出版事項: (2008)

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
著者:: Jan Hendrik van Weerd, 等
出版事項: (2020-07-01)

Developmental origin, growth, and three-dimensional architecture of the atrioventricular conduction axis of the mouse heart.
著者:: Aanhaanen, W, 等
出版事項: (2010)

Embryonic Tbx3+ cardiomyocytes form the mature cardiac conduction system by progressive fate restriction
著者:: Mohan, R, 等
出版事項: (2018)

Role of Genetic Variation in Transcriptional Regulatory Elements in Heart Rhythm
著者:: Timo Jonker, 等
出版事項: (2023-12-01)

Epigenetic State Changes Underlie Metabolic Switch in Mouse Post-Infarction Border Zone Cardiomyocytes
著者:: Marie Günthel, 等
出版事項: (2021-10-01)

An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility
著者:: Fernanda M Bosada, 等
出版事項: (2023-01-01)

A single cell transcriptional roadmap of human pacemaker cell differentiation
著者:: Alexandra Wiesinger, 等
出版事項: (2022-10-01)

Identification and Characterization of a Transcribed Distal Enhancer Involved in Cardiac Kcnh2 Regulation
著者:: Malou van den Boogaard, 等
出版事項: (2019-09-01)

Talkin’ ‘bout regeneration: new advances in cardiac regeneration using the zebrafish
著者:: Smith, KA, 等
出版事項: (2020)

Identification and functional characterization of cardiac pacemaker cells in zebrafish.
著者:: Federico Tessadori, 等
出版事項: (2012-01-01)

Unlocking the secrets of the regenerating fish heart: comparing regenerative models to shed light on successful regeneration
著者:: Potts, HG, 等
出版事項: (2021)

Identification of atrial fibrillation associated genes and functional non-coding variants
著者:: Antoinette F. van Ouwerkerk, 等
出版事項: (2019-10-01)

Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models
著者:: Jiuru Li, 等
出版事項: (2022-10-01)

Transcriptional profiling of cells sorted by transcript abundance
著者:: Klemm, Sandy Lee, 等
出版事項: (2015)

Transcript counting in single cells reveals dynamics of rDNA transcription
著者:: Tan, Rui Zhen, 等
出版事項: (2011)

Transcript counting in single cells reveals dynamics of rDNA transcription
著者:: Rui Zhen Tan, 等
出版事項: (2010-04-01)

OccuPeak: ChIP-Seq peak calling based on internal background modelling.
著者:: Bouke A de Boer, 等
出版事項: (2014-01-01)

Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium.
著者:: Mommersteeg, M, 等
出版事項: (2007)

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo
著者:: Joyce C. K. Man, 等
出版事項: (2019-10-01)

Atrial fibrillation: a developmental point of view.
著者:: Mommersteeg, M, 等
出版事項: (2009)

A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription.
著者:: Harm van Bakel, 等
出版事項: (2013-05-01)

Investigations into transcription and transcripts in Saccharomyces cerevisiae
著者:: Fischl, H
出版事項: (2015)

Transcriptional and Post-Transcriptional Regulation of Autophagy
著者:: Qiuqin Ma, 等
出版事項: (2022-01-01)

Transcription Factors in Cartilage Homeostasis and Osteoarthritis
著者:: Margot Neefjes, 等
出版事項: (2020-09-01)

Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal
著者:: Marie Günthel, 等
出版事項: (2021-04-01)

Extraordinary model systems for regeneration
著者:: Accorsi, A, 等
出版事項: (2024)

Found: the elusive ANTAR transcription antiterminator.
著者:: Valley Stewart, 等
出版事項: (2012-01-01)

A complex network of transcription factors and epigenetic regulators involved in bovine leukemia virus transcriptional regulation
著者:: Estelle Plant, 等
出版事項: (2023-06-01)

Transcriptional Response of Burkholderia cenocepacia H111 to Severe Zinc Starvation
著者:: James Paul Barnett
出版事項: (2023-09-01)

Validating Transcripts with Probes and Imaging Technology
著者:: Itzkovitz, Shaul Shalev, 等
出版事項: (2012)

Transcription factor condensates and signaling driven transcription
著者:: Rajat Mann, 等
出版事項: (2023-12-01)

Transcriptional regulation by competing transcription factor modules.
著者:: Rutger Hermsen, 等
出版事項: (2006-12-01)

BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
著者:: Drake S. Edwards, 等
出版事項: (2020-09-01)

Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework
著者:: B. M. H. Heuts, 等
出版事項: (2022-11-01)

Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium.
著者:: Kamini Kunasegaran, 等
出版事項: (2014-01-01)

Discordant genome assemblies drastically alter the interpretation of single-cell RNA sequencing data which can be mitigated by a novel integration method
著者:: Potts, HG, 等
出版事項: (2022)

Atrioventricular Block in Children
著者:: Igor A. Kovalev, 等
出版事項: (2018-12-01)

Reflex Atrioventricular Block
著者:: Richard Sutton
出版事項: (2020-04-01)

Bloqueio atrioventricular congênito
著者:: José Mário Baggio Junior, 等
出版事項: (2017-07-01)