Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.
Bibliografiske detaljer
| Main Authors: |
Schlemminger, I,
Mole, D,
McNeill, L,
Dhanda, A,
Hewitson, K,
Tian, Y,
Ratcliffe, P,
Pugh, C,
Schofield, C |
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| Format: | Journal article
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| Sprog: | English |
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| Udgivet: |
2003
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