Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2003
|