A selective N-type Ca(2+)-channel blocker prevents CA1 injury 24 h following severe forebrain ischemia and reduces infarction following focal ischemia.

SNX-111 (NEUREX Corporation, Menlo Park, CA, U.S.A.) an omega-conopeptide, was tested for cytoprotection following normothermic ischemia using both a four-vessel occlusion model of severe forebrain ischemia and a model of transient middle cerebral artery occlusion focal ischemia. Adult male Wistar r...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Buchan, A, Gertler, S, Li, H, Xue, D, Huang, Z, Chaundy, K, Barnes, K, Lesiuk, H
التنسيق: Journal article
اللغة:English
منشور في: 1994