Ultrasensitive detection and phenotyping of CD4+ T cells with optimized HLA class II tetramer staining.
HLA class I tetramers have revolutionized the study of Ag-specific CD8+ T cell responses. Technical problems and the rarity of Ag-specific CD4+ Th cells have not allowed the potential of HLA class II tetramers to be fully realized. Here, we optimize HLA class II tetramer staining methods through the...
Main Authors: | , , , , , , , , , |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2005
|