Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate
Triazole-carboxylic acids related to D-glucose and D-galactose may be prepared by intramolecular [1,3]-dipolar cycloadditions of azides to unsaturated esters, followed by bromine oxidation of the resulting triazoline. Such materials may provide a series of anionic mimics of carbohydrates.
Dades bibliogràfiques
| Autors principals: |
Krulle, T,
delaFuente, C,
Pickering, L,
Aplin, RT,
Tsitsanou, K,
Zographos, SE,
Oikonomakos, N,
Nash, R,
Griffiths, R,
Fleet, G |
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| Format: | Journal article
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| Idioma: | English |
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| Publicat: |
1997
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