The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice.

The use of immunosuppressive drugs in the management of autoimmunity penalizes a large part of the immune system for the misdemeanors of a small minority of T cells. An ideal form of therapy would be one in which it were possible to render the immune system tolerant of the inciting antigens with min...

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Bibliographic Details
Main Authors: Hutchings, P, O'Reilly, L, Parish, N, Waldmann, H, Cooke, A
Format: Journal article
Language:English
Published: 1992