Dose-finding quantitative 18F-FDG PET imaging study with the oral pan-AKT inhibitor GSK2141795 in patients with gynecological malignancies

AKT (a serine/threonine-specific protein kinase) regulates many cellular processes contributing to cytotoxic drug resistance. This study’s primary objective examined the relationship between GSK2141795, an oral, pan-AKT inhibitor, and FDG-PET markers of glucose metabolism in tumor tissue to determin...

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Bibliographic Details
Main Authors:	Gungor, H, Saleem, A, Babar, S, Dina, R, El-Bahrawy, M, Curry, E, Rama, N, Chen, M, Pickford, E, Agarwal, R, Blagden, S, Carme, S, Salinas, C, Madison, S, Krachey, E, Santiago-Walker, A, Smith, D, Morris, S, Stronach, E, Gabra, H
Format:	Journal article
Published:	Society of Nuclear Medicine 2015

Dose-finding quantitative 18F-FDG PET imaging study with the oral pan-AKT inhibitor GSK2141795 in patients with gynecological malignancies

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