Understanding the role of the SNM1B and EXD2 in DNA damage repair

Understanding the role of the SNM1B and EXD2 in DNA damage repair

<p>Unrepaired, or misrepaired, DNA damage can be carcinogenic or mutagenic; thus functional DNA damage repair pathways are essential for the safeguarding of the genome.</p> <p>SNM1B is a 5’ to 3’ exonuclease implicated in the repair of damaged DNA, particularly the repair of inters...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Baddock, H
Awduron Eraill:	McHugh, P
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2017

Eitemau Tebyg

The SNM1A DNA repair nuclease
gan: Baddock, HT, et al.
Cyhoeddwyd: (2020)

Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
gan: Sengerová, B, et al.
Cyhoeddwyd: (2012)

Structure and inhibition of the human SNM1a and SNM1b/Apollo DNA repair exonucleases
gan: Lee, S
Cyhoeddwyd: (2015)

EXD2 promotes homologous recombination by facilitating DNA end resection
gan: Niedzwiedz, W, et al.
Cyhoeddwyd: (2016)

A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A
gan: Doherty, W, et al.
Cyhoeddwyd: (2019)

SNM1A is crucial for efficient repair of complex DNA breaks in human cells
gan: Swift, L, et al.
Cyhoeddwyd: (2024)

Cephalosporins inhibit human metallo β-lactamase fold DNA repair nucleases SNM1A and SNM1B/apollo
gan: Lee, S, et al.
Cyhoeddwyd: (2016)

SNM1A is crucial for efficient repair of complex DNA breaks in human cells
gan: Lonnie P. Swift, et al.
Cyhoeddwyd: (2024-06-01)

The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair
gan: Fenna Hensen, et al.
Cyhoeddwyd: (2018-03-01)

Exploring the binding pockets of the DNA damage repair enzyme SNM1A through nucleobase modification
gan: Ellen M. Fay, et al.
Cyhoeddwyd: (2023-01-01)

Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
gan: Hazrati, A, et al.
Cyhoeddwyd: (2008)

Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target
gan: Bielinski, M, et al.
Cyhoeddwyd: (2024)

The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities
gan: McHugh, P, et al.
Cyhoeddwyd: (2015)

Squaramide‐based 5’‐phosphate replacements bind to the DNA repair exonuclease SNM1A
gan: Dürr, E, et al.
Cyhoeddwyd: (2018)

Human SNM1a and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair
gan: Wang, A, et al.
Cyhoeddwyd: (2011)

Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.
gan: Wang, A, et al.
Cyhoeddwyd: (2011)

The SNM1/Pso2 family of ICL repair nucleases: from yeast to man.
gan: Cattell, E, et al.
Cyhoeddwyd: (2010)

EXD2 - a new player in the DSB resection team
gan: Niedzwiedz, W, et al.
Cyhoeddwyd: (2016)

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
gan: Iyama, T, et al.
Cyhoeddwyd: (2015)

Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A
gan: Eva-Maria Dürr, et al.
Cyhoeddwyd: (2021-01-01)

DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase.
gan: Barber, L, et al.
Cyhoeddwyd: (2005)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
gan: Newman, J
Cyhoeddwyd: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
gan: Gileadi, O
Cyhoeddwyd: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
gan: Newman, J
Cyhoeddwyd: (2018)

Robust single-cell DNA methylome profiling with snmC-seq2
gan: Chongyuan Luo, et al.
Cyhoeddwyd: (2018-09-01)

Identification of Bioactive SNM1A Inhibitors
gan: Beverlee Buzon, et al.
Cyhoeddwyd: (2021-03-01)

EXD2: A new regulator of mitochondrial translation and potential target for cancer therapy
gan: Travis H. Stracker
Cyhoeddwyd: (2018-05-01)

A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family
gan: Baddock, HT, et al.
Cyhoeddwyd: (2021)

Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription
gan: Alely Villarreal-Puente, et al.
Cyhoeddwyd: (2024-07-01)

Variations in EXD3 caused congenital cataracts in three Chinese families
gan: Lihua Cao, et al.
Cyhoeddwyd: (2023-05-01)

Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity
gan: Gustavo Jiménez-Mejía, et al.
Cyhoeddwyd: (2022-05-01)

Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress
gan: Jérémy Sandoz, et al.
Cyhoeddwyd: (2023-01-01)

Elevated levels of autoantibodies against EXD2 and PHAX in the sera of patients with chronic thromboembolic pulmonary hypertension.
gan: Akira Naito, et al.
Cyhoeddwyd: (2019-01-01)

SNM Children‘s Museum: The first five years (2010-2015) (Detské múzeum SNM v Bratislave v rokoch 2010 – 2015)
gan: Juraj Kucharík
Cyhoeddwyd: (2016-03-01)

The eukaryotic Pso2/Snm1/Artemis proteins and their function as genomic and cellular caretakers
gan: D. Bonatto, et al.
Cyhoeddwyd: (2005-03-01)

MAXIMUM URETHRAL CLOSURE PRESSURE AS A PREDICTOR OF SUCCESS IN SNM
gan: C Fontaine, et al.
Cyhoeddwyd: (2023-09-01)

Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity
gan: Ronan Broderick, et al.
Cyhoeddwyd: (2023-04-01)

Designing an online course using an EXD model: A case of Human–Computer Interaction undergraduate course
gan: Lintang Matahari Hasani, et al.
Cyhoeddwyd: (2024-06-01)

The role of TIRR in DNA damage and repair
gan: Ketley, R
Cyhoeddwyd: (2022)

Role of Nicotinamide in DNA Damage, Mutagenesis, and DNA Repair
gan: Devita Surjana, et al.
Cyhoeddwyd: (2010-01-01)