Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase.

2-Oxoglutarate and iron dependent oxygenases have potential for the stereoselective hydroxylation of amino acids and related compounds. The biochemical and kinetic properties of recombinant γ-butyrobetaine hydroxylase from human and Pseudomonas sp. AK1 were compared. The results reveal differences b...

全面介紹

書目詳細資料
Main Authors: Rydzik, A, Leung, I, Kochan, G, Loik, N, Henry, L, McDonough, M, Claridge, T, Schofield, C
格式: Journal article
語言:English
出版: Royal Society of Chemistry 2014