Genetics of a multifactorial disease: autoimmune type 1 diabetes mellitus.

1. Three non-major histocompatibility complex genes, Idd-3, Idd-4 and Idd-5, that influence the onset of autoimmune type 1 diabetes in the non-obese diabetic mouse have been located on chromosomes 3, 11 and 1. 2. In undertaking this study, a new map of the mouse genome has been created from polymera...