Assessing oxidative stress in tumors by measuring the rate of hyperpolarized [1-13C] dehydroascorbic acid reduction using 13C magnetic resonance spectroscopy

Rapid cancer cell proliferation promotes the production of reducing equivalents, which counteract the effects of relatively high levels of reactive oxygen species. Reactive oxygen species levels increase in response to chemotherapy and cell death, whereas an increase in antioxidant capacity can conf...

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Xehetasun bibliografikoak
Egile Nagusiak: Timm, KN, Hu, D-E, Williams, M, Wright, AJ, Kettunen, MI, Kennedy, BWC, Larkin, TJ, Dzien, P, Marco-Rius, I, Bohndiek, SE, Brindle, KM
Formatua: Journal article
Hizkuntza:English
Argitaratua: American Society for Biochemistry and Molecular Biology 2016