Probing distance and electrical potential within a protein pore with tethered DNA.

DNA molecules tethered inside a protein pore can be used as a tool to probe distance and electrical potential. The approach and its limitations were tested with alpha-hemolysin, a pore of known structure. A single oligonucleotide was attached to an engineered cysteine to allow the binding of complem...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Howorka, S, Bayley, H
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2002