CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.

BACKGROUND: Cryptococcal meningitis (CM) is a severe AIDS-defining illness with 90-day case mortality as high as 70% in sub-Saharan Africa, despite treatment. It is the leading cause of death in HIV patients in Asia and Africa.No major advance has been made in the treatment of CM since the 1970s. Th...

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Bibliographic Details
Main Authors:	Day, N, Imran, D, Ganiem, A, Tjahjani, N, Wahyuningsih, R, Adawiyah, R, Dance, D, Mayxay, M, Newton, P, Phetsouvanh, R, Rattanavong, S, Chan, A, Heyderman, R, van Oosterhout, J, Chierakul, W, Day, J, Kamali, A, Kibengo, F, Ruzagira, E, Gray, A, Lalloo, D, Beardsley, J, Binh, T, Chau, T, Chau, N, Cuc, N, Farrar, J, Hien, T, Van Kinh, N, Merson, L, Phuong, L, Tho, L, Thuy, P, Thwaites, G, Wertheim, H, Wolbers, M
Format:	Journal article
Language:	English
Published:	BioMed Central 2014

CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.

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