Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic disease associated with inflammation and destruction of bone and cartilage. Although inhibition of TNFα is widely used to treat RA, a significant number of patients do not respond to TNFα blockade, and therefore there is a compelling need to cont...

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Bibliographic Details
Main Authors: Gompels, L, Malik, N, Madden, L, Jin, P, Feldmann, M, Shepard, H, Paleolog, E
Format: Journal article
Language:English
Published: BioMed Central 2011