Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

RNA-directed antisense and interference therapeutics are a promising treatment option for cancer. The demonstration of depletion of target proteins within human tumors in vivo using validated methodology will be a key to the application of this technology. Here, we present a flow cytometric-based ap...

全面介绍

书目详细资料
Main Authors: Olsen, A, Davies, J, Medley, L, Breen, D, Talbot, D, McHugh, P
格式: Journal article
语言:English
出版: Nature Publishing Group 2012