Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

RNA-directed antisense and interference therapeutics are a promising treatment option for cancer. The demonstration of depletion of target proteins within human tumors in vivo using validated methodology will be a key to the application of this technology. Here, we present a flow cytometric-based ap...

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Hlavní autoři: Olsen, A, Davies, J, Medley, L, Breen, D, Talbot, D, McHugh, P
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2012