Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma.

AIMS: The coordinated expression of the Notch ligands Delta-like 4 (Dll4) and Jagged (Jag)1 is believed to define appropriate endothelial sensitivity to vascular endothelial growth factor (VEGF). Preclinical data suggest that Dll4-Notch signalling may confer resistance to anti-VEGF therapy with beva...

Полное описание

Библиографические подробности
Главные авторы: Jubb, A, Browning, L, Campo, L, Turley, H, Steers, G, Thurston, G, Harris, A, Ansorge, O
Формат: Journal article
Язык:English
Опубликовано: 2012