DNA-protein crosslink proteolysis repair

Proteins that are covalently bound to DNA constitute a specific type of DNA lesion known as DNA-protein crosslinks (DPCs). DPCs represent physical obstacles to the progression of DNA replication. If not repaired, DPCs cause stalling of DNA replication forks that consequently leads to DNA double-stra...

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Bibliographic Details
Main Authors: Vaz, B, Popovic, M, Ramadan, K
Format: Journal article
Language:English
Published: Elsevier 2017