DNA-protein crosslink proteolysis repair
Proteins that are covalently bound to DNA constitute a specific type of DNA lesion known as DNA-protein crosslinks (DPCs). DPCs represent physical obstacles to the progression of DNA replication. If not repaired, DPCs cause stalling of DNA replication forks that consequently leads to DNA double-stra...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
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