DNA-protein crosslink proteolysis repair

Proteins that are covalently bound to DNA constitute a specific type of DNA lesion known as DNA-protein crosslinks (DPCs). DPCs represent physical obstacles to the progression of DNA replication. If not repaired, DPCs cause stalling of DNA replication forks that consequently leads to DNA double-stra...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Vaz, B, Popovic, M, Ramadan, K
Format: Journal article
Sprog:English
Udgivet: Elsevier 2017