Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib.

The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM). Although bortezomib is known to be a selective proteasome inhibitor, the downstream mechanisms of cytotoxicity and...

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Dades bibliogràfiques
Autors principals: Shringarpure, R, Catley, L, Bhole, D, Burger, R, Podar, K, Tai, Y, Kessler, B, Galardy, P, Ploegh, H, Tassone, P, Hideshima, T, Mitsiades, C, Munshi, N, Chauhan, D, Anderson, K
Format: Journal article
Idioma:English
Publicat: 2006