Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib.

The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM). Although bortezomib is known to be a selective proteasome inhibitor, the downstream mechanisms of cytotoxicity and...

Полное описание

Библиографические подробности
Главные авторы: Shringarpure, R, Catley, L, Bhole, D, Burger, R, Podar, K, Tai, Y, Kessler, B, Galardy, P, Ploegh, H, Tassone, P, Hideshima, T, Mitsiades, C, Munshi, N, Chauhan, D, Anderson, K
Формат: Journal article
Язык:English
Опубликовано: 2006